Nerve agents are scary stuff. They are among the most deadly substances on earth, yet can be odorless, tasteless and difficult to detect. But researchers now report in ACS Central Science that they have adapted building materials normally associated with children's toys and a cell phone to help sense these compounds. The new method can sensitively detect these poisons, quantify the amount and distinguish between different classes present at contaminated sites.

Because nerve agents shut off enzymes that control the body's nervous system function, death comes quickly - in minutes or even seconds. Thus, it's important to detect these compounds quickly so that swift action can be taken. But in addition to taking too long, current methods require expensive instruments and are poorly suited for field use.

Complicating matters, there are two main categories of nerve agents, requiring different decontamination protocols. Existing tools are not effective in differentiating between these classes, which is important because one is more toxic and less volatile than the other, leading to a greater potential for mass harm.

Eric Anslyn, Edward M. Marcotte, and colleagues sought to develop an instrumental set-up and method that addressed these issues and would be simple to use.

The researchers developed a cascade of reactions that amplify an optical signal that results from a byproduct of a decomposition reaction of the nerve agents. The resulting mixtures change their color and intensity of emission relative to the amount of chemical weapon present.

This visual change of emission provides a sensitive test that can be read using common, inexpensive household and laboratory items. The simple design features a LEGO box with a template to guide a smartphone's placement on a stage, where the phone acts as the instrument's camera.

The only other necessary components are a UV/visible lamp and a standard 96-well test plate. Free software helps analyze the resulting image. To encourage wide adoption of their technology, the researchers uploaded their analytic code, image guides, and a demonstration video to GitHub.

Research paper

Related Links
American Chemical Society
The Long War - Doctrine and Application

Tweet

Thanks for being here; We need your help. The SpaceDaily news network continues to grow but revenues have never been harder to maintain. With the rise of Ad Blockers, and Facebook - our traditional revenue sources via quality network advertising continues to decline. And unlike so many other news sites, we don't have a paywall - with those annoying usernames and passwords. Our news coverage takes time and effort to publish 365 days a year. If you find our news sites informative and useful then please consider becoming a regular supporter or for now make a one off contribution.
SpaceDaily Contributor $5 Billed Once credit card or paypal		SpaceDaily Monthly Supporter $5 Billed Monthly paypal only

IS threatens to execute 6 Iraqis unless women prisoners freed
Baghdad (AFP) June 23, 2018
The Islamic State group on Saturday threatened to execute within three days six Iraqi men it said it is holding, unless authorities in Baghdad release Sunni Muslim female prisoners. The threat came in a video released by the jihadists' Amaq propaganda agency, showing six men, their faces covered in bruises. IS said the men were abducted members of the Iraqi police and the Hashed al-Shaabi paramilitary force, which played a key role in Iraq's war against the jihadists. Iraq declared victory o ... read more